Searchable abstracts of presentations at key conferences on calcified tissues

ba0002p40 | (1) | ICCBH2013

Altered bone metabolism in obese children: the pathogenic role of adipocytokines and inflammation

Abramowicz Pawel , Konstantynowicz Jerzy , Werpachowska Irena , Jamiolkowski Jacek , Kaczmarski Maciej , Piotrowska-Jastrzebska Janina

Objective: Associations between childhood obesity and disturbed bone metabolism have been extensively studied. Both RANK/RANKL/OPG and adipocytokines are involved in bone metabolism in obese individuals although published data remain inconsistent. Some reports show evidence of protective role of adiposity in the maintenance of skeletal mass, whereas others fail to support this evidence or even demonstrate an increased fragility. The aim of the study was to assess bone metaboli...